Sickle Cell Disease An Overview - 800 Words

Sickle Cell Disease: An Overview Sickle Cell Disease is a hereditary issue in which the body produces Sickled formed red platelets. In Sickle cell disease, or SCD, the hemoglobin in red platelets gathers together. This in turn causes red platelets to get firm and C-formed. The most well-known signs and indications of SCD are anemia and pain through the body. Sickle Cell Disease occurs most commonly in individuals whose families descend from West Africa, South or Central America (particularly Panama), Caribbean islands, Mediterranean nations, (for example, Turkey, Greece, and Italy), India, and Saudi Arabia. In the United States, it’s estimated that Sickle cell affects between 70,000–100,000 individuals, predominately African†¦show more content†¦The condition creates when Sickle-molded red platelets hinder move through minor vessels to the midsection, mid-region, joints, and once in a while bones, bringing on great torment and distress. Torment may change in force and can keep going for a couple of hours to a couple of weeks. Some individuals encounter just a couple of scenes of torment. Others encounter twelve or more emergencies a year. In the event that an emergency is serious enough, it may oblige hospitalization. A significant muddling of Sickle cell frailty is oxygen hardship in blood and organs. The accompanying portrays a portion of the other wellbeing issues of those hit with SCD: Stroke. A stroke can happen if Sickle cells piece blood stream to a region of your mind. Intense midsection syndrome. This life-debilitating entanglement of Sickle cell sickliness causes midsection torment, fever and trouble relaxing. Pulmonary hypertension. Shortness of breath and trouble breathing are regular manifestations of this condition, which might be deadly. Organ harm. Sickle cells may obstruct blood move through veins, instantly denying an organ of blood and oxygen. Constant hardship of oxygen-rich blood can harm nerves and organs in your body, including your kidneys, liver and spleen. Lack of sight. Minor veins that supply your eyes can get obstructed by Sickle cells. This can harm the retina, the segment of the eye that techniques visual pictures, about whether. Gallstones. TheShow MoreRelatedCell Signaling Essay1583 Words   |  7 PagesDefects of Cell Signaling Over the past semester in cell biology, determining protein structure and functions of gene sequences have been some important discussions in class. On this discussion, many people will agree that the defects from the protein structure and gene sequences such as cell-signaling are the main factors of human disease. When it comes to the topic of human disease breast cancer and sickle cell anemia have been the most prevalent. The importance of these topics in reference toRead MoreA Research Study : The Haemoglobinopathy, A Severe Blood Disorder And Its Effects On African People1020 Words   |  5 Pagesanaemia due to sickled red blood cells however in 1949 Linus Pauling identified that there was a molecular difference in the haemoglobin of a sickled and wild-type individual (Gabriel, A. and Przybylski, J., 2010). Ingram V. made the further observation that a single nucleotide polymorphism (SNP) resulting in valine instead of glutamic acid led to the conformational change in haemoglob in (Gabriel, A. and Przybylski, J., 2010). Although there is an increase of the disease in the UK, SCD has generallyRead MoreSickle Cell Anemi A Group Of Diseases Essay1101 Words   |  5 PagesSickle Cell Anemia Introduction: Sickle cell disease is a group of diseases in which the affected individual has at least one copy of hemoglobin S (HbS). Sickle cell anemia is a type of sickle cell disease in which the patient inherits 2 copies of hemoglobin S (genotype HbSS). There are other examples of sickle cell disease; they include- HbAS, HbSC, and HbS beta thalassemia (National Heart, Lung, and Blood Institute). The focus of this article would be on Sickle cell anemia.Read MoreThe Stem Cell Therapy ( Iusct )1641 Words   |  7 PagesIntrauterine stem cell therapy (IUSCT) refers to treatment of a variety of fetal genetic disorders thought transplantation of either allogenic or genetically modified autologous stem cells. Stem cells become incorporated into the recipient tissue to start proliferation and differentiation through their pluripotent or multipotent potential to compensate for the missing or defective protein. This could be useful in treating fetal genetic disorders which are consid ered to be perinatally lethal or associatedRead MoreSource Of Information : Mother And Patient2081 Words   |  9 Pages Her vitals in the ED were as follows: BP 133/89 HR 106 RR 20 T 99.1 The ED work-up results were as follows: CBC: 18.83 336 Neutrophils 81% Bands 4% Lymphocytes 11% BMP: 144/4.5/103/23/5/0.600%) The results indicated that this patient had sickle cell beta thalassemia positive anemia. The results were never disclosed to the family and now the patient was experiencing her first vaso-occlusive crisis likely precipitated by infection (pneumonia). Throughout the hospital stay, the patient experiencedRead MoreCauses And Treatment Of Sickle Cell Anemia1814 Words   |  8 PagesApproximately 70,000-100,000 Americans have sickle cell anemia, the most common form of an inherited blood disorder that causes the production of abnormal hemoglobin, a protein that attaches to oxygen in the lungs and carries it to all parts of the body.1 Sickle cell anemia is a inherited disorder which causes the manifestation of unreliable hemoglobin resulting unevenly shaped red blood cells, recognized as sickle cells. People with sickle cell disease have red blood cells that have mostly hemoglobin S,Read MoreCan Sickle Cell Anaemia Be Cured?3101 Words   |  13 PagesCan Sickle Cell Anaemia be Cured E ffectively in Adults? 1.1 Identification of a Biological Issue Sickle cell anaemia is a disorder affecting the red blood cells and up to 100,000 people are estimated to have the disease in the USA (Centre for Disease Control). Due to a genetic mutation in the gene responsible for the production of haemoglobin (MayoClinic, 2014) the red blood cells, which are usually a biconcave disk in shape, become sickle (bent) shaped (Figure 1) and the haemoglobin that the redRead MoreWhat Qualities, Skills, Talents, And Experiences Of A Good Health Care Practitioner?1418 Words   |  6 Pagescoursework that I have taken reflects my interest in the intersection between biomedical science and its applications through an anthropological lens. For example, I have performed public health research on biological and social factors influencing sickle cell disease with the Public Health Advanced Summer Education program. I also enjoy translating the knowledge I obtained into teachings that will impact others. I was a teaching assistant for Shanti Parikh’s co urse, The AIDS Epidemic: Inequalities, EthnographyRead MoreMoringa688 Words   |  3 PagesTop 5 Health benefits of Moringa Tea Overview A lot of people have not been aware about the health benefits of Moringa Oleifera tea. This â€Å"miracle tree† has been around for ages and it has been a powerhouse of a lot of minerals and antioxidant. Its byproducts, Moringa tea, are well known for combating signs of aging and helping in various diseases. It has also been proven that when taken on daily basis, Moringa tea can improve the life of a sickle cell anemia patient. It has proteins that haveRead More5-Azacytidine is a Potential Chemotherapeutic Agents for Cancer1430 Words   |  6 PagesOverview 5-Azacytidine is a chemical analogue of cytidine, a nucleoside present in DNA and RNA with antineoplastic activity. It is sold under the brand name Vidaza. The drug was first synthesized in Czechoslovakia as potential chemotherapeutic agents for cancer. It is an inhibitor of DNA methylation and was approved by the US FDA for the treatment of Myelodysplastic syndromes (MDS) in May 2004. MDS are diseases caused by abnormalities in the blood-forming cells of the bone marrow, which result in